Good drinks. Good people. Good times.
Hours of Operation
Wednesday & Thurs: 4 pm - 12 am
Friday & Saturday: 4 pm - 2 am
CLOSED: Sunday - Tuesday
Call (919) 680-0570
You pick 'em, we'll fill it: Mix & Match 6 packs
Top selling beers
Bottles of Wine
Since 2013, 106 Main has become a staple in downtown Durham. From our vast beer selection to our extensive liquor collection, there's a drink to satisfy your thirst! We have everything you need to have a great night out or come see us during the day!
We’re dedicated to making sure your time with us is unlike anything else you’ve experienced. Our professional crew behind the bar has carefully curated a list of world-renowned drinks that leave your mouth buzzing with layers of flavor. Don’t believe us? Come on by and see for yourself.
Due to Covid-19 we had to close in March 2020. We are fortunate to be back and open! Come see us with full service including spirits, cocktails, and specialty drinks.